Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27746262

CCC1(CC)c2ccccc2-c2ccc(-c3ccccc3)c(-c3ccccc3)c21.N

nearest known ligand 0.36

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.36
PGR P06401 2/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDK2 Q15119 4/20 0.32
DHFR P00374 1/20 0.30
HEXA P06865 1/20 0.30
HEXB P07686 1/20 0.30
ELANE P08246 1/20 0.30
HNF4A P41235 1/20 0.30
DPP4 P27487 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28781070 0.91 ELANE (0.36) APEX1PGRPDCD1CD274PDK2
Ammonia Solution, Strong SCHEMBL27746527 0.84 KCNQ2 (0.36) APEX1PDCD1CD274THRBTDP1
Ammonia Solution, Strong SCHEMBL27746235 0.83 ALDH1A1 (0.33) PDCD1CD274THRBTDP1PDK2
SCHEMBL23295611 0.81 MMP2 (0.38) APEX1TDP1PDK2DHFR
Ammonia Solution, Strong SCHEMBL27766921 0.81 MMP2 (0.36) APEX1PDCD1CD274THRBTDP1
SCHEMBL6680362 0.80 APEX1 (0.35) APEX1PGRPDCD1CD274THRB
Ammonia Solution, Strong SCHEMBL27767164 0.80 PDK2 (0.33) PGRPDCD1CD274PDK2
SCHEMBL28120030 0.80 PGR (0.33) APEX1PGRPDCD1CD274DHFR
Ammonia Solution, Strong SCHEMBL3793717 0.79 ALDH1A1 (0.35) PGRPDCD1CD274THRBTDP1
Biphenyl SCHEMBL27967333 0.77 APEX1 (0.46) APEX1PGRPDCD1CD274THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101904028-A organic electroluminescent element IDEMITSU KOSAN CO 2010-12-01 CN disclosed
CN-101473464-A Organic electroluminescent element using heterocyclic aromatic amine derivative IDEMITSU KOSAN CO (JP) 2009-07-01 CN disclosed