Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 6/20 | 0.47 |
| ▸ | ATP4B | P51164 | 6/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609839 | 0.85 | MAPT (0.44) | ATP4AATP4BGSTO1PLAULMNA | |
| SCHEMBL3608371 | 0.82 | GSTO1 (0.64) | ATP4AATP4BGSTO1LMNAALDH1A1 | |
| SCHEMBL30660073 | 0.82 | GSTO1 (0.64) | ATP4AATP4BGSTO1LMNAALDH1A1 | |
| SCHEMBL3612827 | 0.82 | ATP4A (0.47) | ATP4AATP4BGSTO1PLAULMNA | |
| SCHEMBL3609963 | 0.82 | GSTO1 (0.61) | ATP4AATP4BGSTO1VCPSMN1; SMN2 | |
| SCHEMBL11239260 | 0.82 | ATP4A (0.47) | ATP4AATP4BGSTO1PLAULMNA | |
| SCHEMBL3610620 | 0.81 | ATP4A (0.49) | ATP4AATP4BGSTO1PLAUKMT2A | |
| SCHEMBL3597985 | 0.81 | ATP4A (0.61) | ATP4AATP4BGSTO1PLAULMNA | |
| SCHEMBL3600274 | 0.77 | VCP (0.64) | ATP4AATP4BKMT2AVCPMEN1 | |
| SCHEMBL3603436 | 0.77 | MEN1 (0.61) | GSTO1LMNAALDH1A1KMT2AVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466692-A | Thiazol-guanidine derivatives useful as a (beta) - related pathologies | ASTRAZENECA AB (SE) | 2009-06-24 | — | — | CN | claimed |
| CN-101466692-A | Thiazol-guanidine derivatives useful as a (beta) - related pathologies | ASTRAZENECA AB (SE) | 2009-06-24 | — | — | CN | disclosed |