Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776727 | 0.83 | PKM (0.43) | CTSBTDP1MYCNR4A1MEN1 | |
| SCHEMBL5815364 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27768810 | 0.74 | ALDH1A1 (0.44) | TDP1MYCNR4A1MEN1KMT2A | |
| SCHEMBL2835556 | 0.73 | NOTUM (0.30) | NOTUM | |
| SCHEMBL24690273 | 0.72 | CYP3A4 (0.41) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13259099 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL15714404 | 0.70 | GAA (0.41) | TDP1MYCNR4A1MEN1KMT2A | |
| SCHEMBL14468900 | 0.69 | NPC1 (0.37) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7031169 | 0.69 | MYC (0.59) | CTSBTDP1MYCNR4A1MEN1 | |
| SCHEMBL15871992 | 0.69 | TDP1 (0.59) | CTSBTDP1MYCNR4A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101468985-A | 5-(3-aromatic heterocyclic substituted phenyl) tetrazole compounds and anti-HIV/AIDS use thereof | POISON MED INST PLA MED ACAD (CN) | 2009-07-01 | — | — | CN | claimed |
| CN-101468985-A | 5-(3-aromatic heterocyclic substituted phenyl) tetrazole compounds and anti-HIV/AIDS use thereof | POISON MED INST PLA MED ACAD (CN) | 2009-07-01 | — | — | CN | disclosed |