Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179792 | 0.87 | KMT2A (0.48) | ACHEKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL241030 | 0.83 | PORCN (0.42) | ACHEKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL25308002 | 0.83 | ACHE (0.47) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL27529858 | 0.81 | ACHE (0.46) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL27680292 | 0.81 | ACHE (0.46) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL7674985 | 0.80 | LMNA (0.52) | ACHESMN1; SMN2ESR1HIF1AKDM4E | |
| SCHEMBL25262782 | 0.80 | ACHE (0.45) | ACHEKMT2ASMN1; SMN2ESR1HIF1A | |
| SCHEMBL15880687 | 0.79 | KMT2A (0.52) | KMT2AKDM4EUHRF1MAPK1PORCN | |
| Hydrochloric Acid SCHEMBL10529996 | 0.79 | LMNA (0.50) | ACHESMN1; SMN2ESR1HIF1AKDM4E | |
| SCHEMBL10144351 | 0.78 | ACHE (0.47) | ACHEKMT2ASMN1; SMN2ESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495461-A | Novel HIV reverse transcriptase inhibitors | GILEAD SCIENCES INC (US) | 2009-07-29 | — | — | CN | disclosed |