Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769340 | 0.82 | KCNN4 (0.37) | MDM2ALDH1A1LMNAKCNN4TSHR | |
| SCHEMBL27769329 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNAKCNN4TSHRMAPK1 | |
| SCHEMBL27769320 | 0.80 | KCNN4 (0.38) | FABP4FABP5MDM2TP53ALDH1A1 | |
| SCHEMBL27748171 | 0.77 | TRPV1 (0.36) | TP53ALDH1A1LMNAKCNN4P2RX7 | |
| SCHEMBL27748142 | 0.75 | KCNN4 (0.36) | MDM2ALDH1A1LMNAKCNN4TSHR | |
| SCHEMBL27925722 | 0.73 | DHODH (0.39) | ALDH1A1LMNAKCNN4TSHR | |
| SCHEMBL27748148 | 0.72 | KCNN4 (0.37) | FABP4FABP5TP53ALDH1A1KCNN4 | |
| SCHEMBL16875759 | 0.70 | DHODH (0.36) | RIPK1ALDH1A1TSHRDPP4NFE2L2 | |
| SCHEMBL27925737 | 0.70 | NPC1 (0.39) | FABP4FABP5TP53ALDH1A1KCNN4 | |
| SCHEMBL27769338 | 0.69 | ALDH1A1 (0.39) | ALDH1A1LMNAKCNN4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479250-B | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE | 2013-05-22 | — | — | CN | disclosed |
| CN-101479250-A | Tetrazole-substituted arylamides | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |