SCHEMBL27748876

SCHEMBL27748876

[CH2]C(C)([S+]=O)c1ncccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 12/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HTT P42858 1/20 0.34
TRPV1 Q8NER1 1/20 0.32
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.31
CASP3 P42574 1/20 0.31
KMT2A Q03164 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SLC40A1 Q9NP59 1/20 0.31
MET P08581 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1334085 0.80 LMNA (0.36) NFE2L2SMN1; SMN2TRPV1LMNAMEN1
SCHEMBL179292 0.75 TRPV1 (0.37) NFE2L2TRPV1LMNAKMT2A
SCHEMBL369947 0.72 TRPV1 (0.35) NFE2L2TRPV1
SCHEMBL18668145 0.72 HSD11B1 (0.39) NFE2L2SMN1; SMN2HTTTRPV1LMNA
SCHEMBL29724855 0.72 DPP4 (0.36) NFE2L2SMN1; SMN2HTTTRPV1LMNA
SCHEMBL3866262 0.71 JAK2 (0.33) NFE2L2TRPV1LMNA
SCHEMBL30592740 0.71 TDP1 (0.39) NFE2L2SMN1; SMN2HTTLMNAMEN1
SCHEMBL3257764 0.71 TDP1 (0.39) NFE2L2SMN1; SMN2HTTLMNAMEN1
SCHEMBL365596 0.70 SMN1; SMN2 (0.42) SMN1; SMN2HTTTRPV1LMNAMEN1
SCHEMBL20609516 0.69 TDP1 (0.40) NFE2L2SMN1; SMN2HTTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed
CN-101679377-A Heterocyclic hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO 2010-03-24 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed