Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | GRM8 | O00222 | 12/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 12/20 | 0.34 |
| ▸ | GRM6 | O15303 | 7/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748853 | 1.00 | ADRB2 (0.37) | ADRB2HPDGRM8GRM4GRM6 | |
| SCHEMBL1185442 | 0.83 | ADRB2 (0.38) | ADRB2HPDGRM8GRM4GRM6 | |
| SCHEMBL2582039 | 0.83 | ADRB2 (0.38) | ADRB2HPDGRM8GRM4GRM6 | |
| Hydrochloric Acid SCHEMBL1185967 | 0.82 | ADRB2 (0.40) | ADRB2HPDGRM8GRM4GRM6 | |
| SCHEMBL27748852 | 0.80 | ADRB2 (0.35) | ADRB2HPDGRM8GRM4GRM6 | |
| SCHEMBL27748906 | 0.80 | ADRB2 (0.35) | ADRB2HPDGRM8GRM4GRM6 | |
| SCHEMBL27696889 | 0.78 | FLT1 (0.47) | HPGDLMNAMAPT | |
| SCHEMBL27716644 | 0.78 | ABCB1 (0.36) | HTTALDH1A1MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL1187604 | 0.76 | HCAR3 (0.41) | ADRB2GRM8GRM4GRM6HTT | |
| SCHEMBL27884642 | 0.76 | MEN1 (0.33) | ADRB2HTTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495463-B | Seven-membered ring compound, production method thereof and pharmaceutical use thereof | DAIICHI SANKYO CO LTD | 2012-08-15 | — | — | CN | disclosed |
| CN-101495463-A | Seven-membered ring compound, production method thereof and pharmaceutical use thereof | ASUBIO PHARMA CO LTD (JP) | 2009-07-29 | — | — | CN | disclosed |