Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828446 | 0.78 | MEN1 (0.37) | MEN1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL28270666 | 0.78 | ITGB1 (0.38) | MEN1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL27828496 | 0.78 | ABCB1 (0.39) | MEN1KMT2APOLBMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL27868165 | 0.77 | TSHR (0.44) | MEN1KMT2APOLBMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL27868166 | 0.77 | TSHR (0.44) | MEN1KMT2APOLBMAPTMAPK1 | |
| SCHEMBL27748907 | 0.76 | ADRB2 (0.37) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL27748853 | 0.76 | ADRB2 (0.37) | MEN1KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL27570720 | 0.72 | ALDH1A1 (0.46) | KMT2AMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL27720989 | 0.72 | GPR35 (0.46) | ALDH1A1HTT | |
| SCHEMBL28158467 | 0.71 | TSHR (0.40) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495463-B | Seven-membered ring compound, production method thereof and pharmaceutical use thereof | DAIICHI SANKYO CO LTD | 2012-08-15 | — | — | CN | disclosed |