Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CPS1 | P31327 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838212 | 0.87 | MEN1 (0.61) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2777908 | 0.87 | CPS1 (0.68) | MEN1KMT2ACPS1HSD11B1 | |
| SCHEMBL1673485 | 0.85 | HSD11B1 (0.70) | MEN1KMT2ACPS1HSD11B1 | |
| SCHEMBL6141006 | 0.84 | L3MBTL1 (0.61) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| SCHEMBL13390919 | 0.84 | HTR1F (0.57) | MEN1KMT2ACPS1ALDH1A1MAPT | |
| SCHEMBL17938078 | 0.82 | HSD11B1 (0.60) | MEN1KMT2ACPS1HSD11B1 | |
| SCHEMBL28026635 | 0.81 | L3MBTL1 (0.55) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| SCHEMBL28026637 | 0.81 | L3MBTL1 (0.55) | MEN1KMT2ACPS1HSD11B1ALDH1A1 | |
| SCHEMBL28032930 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2ACPS1ALDH1A1MAPT | |
| SCHEMBL8803931 | 0.81 | MEN1 (0.52) | MEN1KMT2ACPS1HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-A1 | NEW HETEROCYCLIC COMPOUNDS | H. Hoffnabb-La Roche Ag (CH) | 2020-10-07 | — | — | EP | disclosed |