Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774895 | 0.84 | KMT2A (0.53) | CCR1HSD11B1KMT2ALMNATSHR | |
| SCHEMBL2780495 | 0.80 | CCR1 (0.55) | CCR1KMT2ALMNATSHR | |
| SCHEMBL2775803 | 0.80 | CCR1 (0.55) | CCR1KMT2ALMNATSHR | |
| SCHEMBL2773596 | 0.80 | CCR1 (0.55) | CCR1KMT2ALMNATSHR | |
| SCHEMBL2774188 | 0.79 | CCR1 (0.57) | CCR1KMT2ALMNATSHR | |
| Hydrochloric Acid SCHEMBL2773460 | 0.79 | HSD11B1 (0.60) | HSD11B1CYP2C19LMNAMGLL | |
| Hydrochloric Acid SCHEMBL2773463 | 0.79 | HSD11B1 (0.60) | HSD11B1CYP2C19LMNAMGLL | |
| SCHEMBL2774900 | 0.79 | CCR1 (0.55) | CCR1HSD11B1CYP2C19KMT2ALMNA | |
| SCHEMBL2775294 | 0.78 | CCR1 (0.53) | CCR1KMT2ALMNATSHR | |
| SCHEMBL10291958 | 0.77 | CCR1 (0.89) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |