Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127853 | 0.87 | KMT2A (0.73) | NR1H4MAPK1HPGDKMT2APPARG | |
| SCHEMBL1032002 | 0.85 | MAPK1 (0.77) | MAPK1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20371784 | 0.84 | ROCK2 (0.60) | MAPK1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1420642 | 0.84 | NR1H4 (0.62) | NR1H4MAPK1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL17373986 | 0.84 | HPGD (0.74) | MAPK1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL13501302 | 0.84 | NR1H4 (0.76) | NR1H4MAPK1HPGDKMT2AALDH1A1 | |
| SCHEMBL27839105 | 0.83 | NPC1 (0.57) | NR1H4HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28792757 | 0.83 | RAB9A (0.57) | NR1H4MAPK1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL13162908 | 0.83 | MAPK1 (0.61) | NR1H4MAPK1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL15600276 | 0.80 | NR1H4 (0.61) | NR1H4MAPK1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490021-B | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2011-11-02 | — | — | CN | disclosed |
| CN-101490021-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-22 | — | — | CN | disclosed |