Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897426 | 0.87 | — | — | |
| SCHEMBL10170023 | 0.81 | TSHR (0.38) | TSHRNFKB1CYP2C19 | |
| SCHEMBL1555233 | 0.79 | TSHR (0.32) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10170322 | 0.77 | TSHR (0.35) | TSHRNFKB1CYP2C19 | |
| SCHEMBL772228 | 0.77 | TSHR (0.35) | TSHRNFKB1CYP2C19 | |
| SCHEMBL537956 | 0.75 | TSHR (0.30) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10170323 | 0.75 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL537957 | 0.75 | TSHR (0.30) | TSHRNFKB1CYP2C19 | |
| SCHEMBL8476820 | 0.75 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL10171052 | 0.75 | TSHR (0.34) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732100-B2 | Preparation of alkaline earth metal-complexed metal bisamides from metal monoamides | BAYER CROPSCIENCE AG (DE) | 2017-08-15 | — | — | US | disclosed |
| US-9663546-B2 | Metal amides of cyclic amines | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-05-30 | — | — | US | disclosed |
| US-9334292-B2 | Alkaline earth metal-complexed metal bisamides | BAYER CROPSCIENCE AG (DE) | 2016-05-10 | — | — | US | disclosed |
| US-20160016977-A1 | ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-21 | — | — | US | disclosed |
| US-20150368277-A1 | PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES | BAYER CROPSCIENCE AG (DE) | 2015-12-24 | — | — | US | disclosed |
| US-8134005-B2 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universitat München (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20100144516-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368277-A1 | PREPARATION OF ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES FROM METAL MONOAMIDES | ASH2L, NAAA, MGAM2 | TSHR 4076/4885NFKB1 2509/4885CYP2C19 2505/4885 |
| US-20160016977-A1 | ALKALINE EARTH METAL-COMPLEXED METAL BISAMIDES | AP1M1, FHIT, AP2M1 | TSHR 4365/4885NFKB1 551/4885CYP2C19 1353/4885 |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | MLX, GLRX3, SFXN3 | TSHR 49/4885NFKB1 3093/4885CYP2C19 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.