Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | HTR1F | P30939 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777481 | 0.83 | HDAC3 (0.35) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL28777651 | 0.70 | HTR6 (0.34) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3619658 | 0.68 | HTR6 (0.62) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL28777480 | 0.68 | HDAC3 (0.36) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL28746133 | 0.67 | ALDH1A1 (0.44) | HTR6CYP3A4 | |
| SCHEMBL3611095 | 0.65 | FABP4 (0.55) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3611374 | 0.63 | HTR6 (0.80) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3622901 | 0.63 | KDM4E (0.58) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3613863 | 0.63 | HTR6 (0.53) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Sulfuric Acid SCHEMBL10585308 | 0.62 | ALDH1A1 (0.36) | HTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |