Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | RECQL | P46063 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881114 | 0.78 | TDP1 (0.45) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL10884603 | 0.78 | ADRB2 (0.56) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL11879993 | 0.78 | TDP1 (0.45) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL11841864 | 0.69 | TDP1 (0.35) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL27751569 | 0.68 | TDP1 (0.53) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL13947847 | 0.67 | TDP1 (0.62) | TDP1KDM4ERECQLMAPTLMNA | |
| Hydrochloric Acid SCHEMBL28575084 | 0.67 | KDM4E (0.34) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL3286354 | 0.67 | TDP1 (0.43) | TDP1KDM4ERECQLMAPTLMNA | |
| SCHEMBL23774421 | 0.66 | TDP1 (0.42) | TDP1KDM4ERECQLMAPTLMNA | |
| Levonordefrin SCHEMBL119171 | 0.66 | TDP1 (1.00) | TDP1KDM4ERECQLMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101366699-A | Novel liposomal aerosol for the controlled release of pharmaceutically active ingredients | UNIV HONG KONG BAPTIST (HK) | 2009-02-18 | — | — | CN | disclosed |