Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.68 |
| ▸ | LTA4H | P09960 | 2/20 | 0.68 |
| ▸ | MMP9 | P14780 | 5/20 | 0.52 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | MMP14 | P50281 | 3/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344865 | 1.00 | ANPEP (0.68) | ANPEPLTA4HMMP9MMP2MMP14 | |
| SCHEMBL21575912 | 0.82 | ANPEP (1.00) | ANPEPLTA4HMMP9MMP2MMP14 | |
| SCHEMBL21715301 | 0.82 | ANPEP (1.00) | ANPEPLTA4HMMP9MMP2MMP14 | |
| SCHEMBL8310215 | 0.81 | LTA4H (0.56) | ANPEPLTA4HFOLH1LMNAALDH1A1 | |
| SCHEMBL12864508 | 0.81 | LTA4H (0.56) | ANPEPLTA4HFOLH1LMNAALDH1A1 | |
| SCHEMBL3175279 | 0.78 | CTRB1 (0.59) | ANPEPLTA4HLMNANAALAD2MAPK1 | |
| SCHEMBL31656407 | 0.78 | CTRB1 (0.59) | ANPEPLTA4HLMNANAALAD2MAPK1 | |
| SCHEMBL15730732 | 0.77 | LMNA (0.53) | ANPEPLTA4HMMP9MMP2MMP14 | |
| SCHEMBL26213571 | 0.77 | LMNA (0.53) | ANPEPLTA4HMMP9MMP2MMP14 | |
| SCHEMBL26724960 | 0.77 | LMNA (0.53) | ANPEPLTA4HMMP9MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101443014-A | Compound (I) | ASTRAZENECA AB (SE) | 2009-05-27 | — | — | CN | disclosed |