Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | YWHAG | P61981 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28797497 | 0.84 | RECQL (0.50) | RECQLLOXLOXL3LOXL2FFAR1 | |
| SCHEMBL8767883 | 0.84 | RECQL (0.53) | RECQLLOXLOXL3LOXL2FFAR1 | |
| SCHEMBL21200364 | 0.81 | RAD52 (0.38) | YWHAGAPPHTTALDH1A1TNKS2 | |
| SCHEMBL28797498 | 0.81 | RECQL (0.46) | RECQLLOXLOXL3LOXL2FFAR1 | |
| SCHEMBL15903067 | 0.78 | LOX (0.53) | RECQLLOXLOXL3LOXL2FFAR1 | |
| SCHEMBL9519051 | 0.78 | MYC (0.40) | YWHAGAPPALDH1A1NR3C2PDE3B | |
| SCHEMBL9518676 | 0.76 | CYP19A1 (0.46) | LOXL2HTTALDH1A1RAD52 | |
| SCHEMBL20943263 | 0.76 | ALDH1A1 (0.54) | FFAR1ALDH1A1 | |
| SCHEMBL29749412 | 0.76 | TSHR (0.50) | FFAR1ALDH1A1 | |
| SCHEMBL15265789 | 0.75 | RECQL (0.46) | RECQLLOXLOXL3LOXL2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374841-A | Spiroimidazole Derivatives as PPAR Modulators | IRM LLC (BM) | 2009-02-25 | — | — | CN | disclosed |