Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2134732 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1ATMRAB9A | |
| SCHEMBL27718312 | 0.82 | TSHR (0.51) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL20719611 | 0.81 | RAD52 (0.38) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL30554484 | 0.81 | RAD52 (0.38) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL20943257 | 0.78 | AOC3 (0.41) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL5717114 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1ATMRAB9A | |
| SCHEMBL31508111 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL1067152 | 0.78 | SIRT2 (0.47) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL20719485 | 0.77 | AOC3 (0.40) | ALDH1A1KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL20719579 | 0.77 | ACACB (0.43) | ALDH1A1MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476829-B1 | BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME | UNIV FUDAN (CN) | 2021-12-15 | — | — | EP | disclosed |
| US-10851050-B2 | Biaryl urea derivative or salt thereof and preparation process and use for the same | FUDAN UNIVERSITY (CN) | 2020-12-01 | — | — | US | disclosed |
| US-20200239411-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME | UNIV FUDAN (CN) | 2020-07-30 | — | — | US | disclosed |
| US-10647665-B2 | Biaryl urea derivative or salt thereof and preparation process and use for the same | FUDAN UNIVERSITY (CN) | 2020-05-12 | — | — | US | disclosed |
| US-20190248737-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME | FUDAN UNIVERSITY (CN) | 2019-08-15 | — | — | US | disclosed |
| EP-3476829-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME | Fudan University (CN) | 2019-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239411-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME | RORC, RORB, RORA | ALDH1A1 644/4885KMT2A 1108/4885MEN1 4267/4885 |
| US-20190248737-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME | RORC, RORB, RORA | ALDH1A1 655/4885KMT2A 1157/4885MEN1 4328/4885 |
| US-10647665-B2 | Biaryl urea derivative or salt thereof and preparation process and use for the same | RORC, RORB, RORA | ALDH1A1 655/4885KMT2A 1157/4885MEN1 4328/4885 |
| US-10851050-B2 | Biaryl urea derivative or salt thereof and preparation process and use for the same | RORC, RORB, RORA | ALDH1A1 644/4885KMT2A 1108/4885MEN1 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.