Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LOX | P28300 | 1/20 | 0.49 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.39 |
| ▸ | MGMT | P16455 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954526 | 0.84 | RECQL (0.47) | RECQLALDH1A1LOXLOXL3LOXL2 | |
| SCHEMBL27752247 | 0.84 | RECQL (0.50) | RECQLALDH1A1LOXLOXL3LOXL2 | |
| SCHEMBL23358049 | 0.84 | RECQL (0.50) | RECQLALDH1A1LOXLOXL3LOXL2 | |
| SCHEMBL28775209 | 0.83 | RECQL (0.53) | RECQLLOXLOXL3LOXL2GRM5 | |
| SCHEMBL501663 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP3A4GRM5NPSR1CA2 | |
| SCHEMBL29882713 | 0.81 | RECQL (0.44) | RECQLALDH1A1LOXLOXL3LOXL2 | |
| SCHEMBL9035534 | 0.80 | ALDH1A1 (0.49) | ALDH1A1CYP3A4NPSR1MEN1KMT2A | |
| SCHEMBL23960219 | 0.80 | ALDH1A1 (0.49) | ALDH1A1CYP3A4KMT2ACA2 | |
| SCHEMBL1886874 | 0.77 | RECQL (0.58) | RECQLALDH1A1LOXLOXL3LOXL2 | |
| SCHEMBL1145877 | 0.77 | LOX (0.57) | RECQLALDH1A1LOXLOXL3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421193-B2 | GPR52 modulators and methods of use | NEUROCRINE BIOSCIENCES, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20230234925-A1 | GPR52 MODULATORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. | 2023-07-27 | — | — | US | disclosed |
| US-20230234925-A1 | GPR52 MODULATORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. | 2023-07-27 | — | — | US | disclosed |
| EP-4139284-A1 | GPR52 MODULATORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021216705-A1 | GPR52 MODULATORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021216705-A1 | GPR52 MODULATORS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |
| EP-0627421-B1 | Method of preparing 2-chloro-pyridinemethanol | CENTRAL GLASS CO LTD (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5440047-A | Method of preparing 2-chloro-pyridinemethanol | CENTRAL GLASS COMPANY, LIMITED (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0627421-A1 | Method of preparing 2-chloro-pyridinemethanol | CENTRAL GLASS COMPANY, LIMITED (JP) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234925-A1 | GPR52 MODULATORS AND METHODS OF USE | GPR52, GPR68, GPR35 | RECQL 2117/4885ALDH1A1 1831/4885LOX 2631/4885 |
| US-12421193-B2 | GPR52 modulators and methods of use | GPR52, GPR68, GPR35 | RECQL 2117/4885ALDH1A1 1831/4885LOX 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.