Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853840 | 0.86 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9743315 | 0.86 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1427228 | 0.86 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1258369 | 0.86 | GAA (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27331577 | 0.85 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28291075 | 0.83 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL13286122 | 0.81 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28479435 | 0.81 | ALOX15 (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL28479433 | 0.81 | ALOX15 (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3064783 | 0.80 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105722829-B | The method of regio-selective synthesis pyrazoles | 伊萨格洛公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-104945325-B | A kind of preparation method of pyrazole carboxylic acid derivant | 浙江永太科技股份有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-104945387-B | Intermediate for preparing pyrazol formic acid derivative | 浙江永太科技股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-106458803-A | Improved process for preparing substituted crotonic acids | 英特维特国际股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-101506173-B | Process for preparing 3-dihalomethylpyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG | 2012-05-30 | — | — | CN | disclosed |
| CN-102099343-A | Process for preparing 1, 3-disubstituted pyrazole carboxylic esters | BASF SE | 2011-06-15 | — | — | CN | disclosed |
| CN-101959840-A | Process for preparing alkyl 2-alkoxymethylene-4,4-difluoro-3-oxobutyrates | BASF SE | 2011-01-26 | — | — | CN | disclosed |
| CN-101506173-A | Process for preparing 3-dihalomethylpyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2009-08-12 | — | — | CN | disclosed |