Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427228 | 1.00 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9743315 | 1.00 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1258369 | 0.90 | GAA (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL13286122 | 0.89 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27753226 | 0.86 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL22475413 | 0.86 | GPR84 (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27331577 | 0.85 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL21551999 | 0.84 | GPR84 (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL21551847 | 0.84 | GPR84 (0.47) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL21552020 | 0.84 | GPR84 (0.47) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4363599-A1 | METHODS TO PRODUCE THERAPEUTIC FORMULATIONS COMPRISING HYDROXYBUTIRATE AND HYDROXYVALERATE, THERAPEUTIC FORMULATIONS AND USES THEREOF | PHB Industrial S.A. (BR) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023278240-A1 | METHODS TO PRODUCE THERAPEUTIC FORMULATIONS COMPRISING HYDROXYBUTIRATE AND HYDROXYVALERATE, THERAPEUTIC FORMULATIONS AND USES THEREOF | PHB INDUSTRIAL S.A. (BR) | 2023-01-05 | — | — | WO | disclosed |
| US-9487551-B2 | Small molecule compounds that control mammal-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-11-08 | — | — | US | disclosed |
| US-9445596-B2 | Small molecule compounds for the control of nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
| US-8273547-B2 | Engineered ketoreductases and methods for producing stereoisomerically pure statins | CODEXIS, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| US-20110251289-A1 | NEW COMPOUNDS FOR THE TREATMENT OF CANCER | CSIR (ZA) | 2011-10-13 | — | — | US | disclosed |
| EP-1904640-B1 | ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE | HOFFMANN LA ROCHE (CH) | 2009-08-19 | — | — | EP | disclosed |
| EP-1904640-A2 | ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE | F. Hoffmann-Roche AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| US-7196234-B2 | Asymmetric reduction of 1,1,1-trifluoroacetone | HOFFMAN-LA ROCHE INC. (US) | 2007-03-27 | — | — | US | disclosed |
| WO-2007006650-A2 | ASYMMETRIC REDUCTION OF 1,1,1-TRIFLUOROACETONE | F. HOFFMANN-LA ROCHE AG (CH) | 2007-01-18 | — | — | WO | disclosed |
| US-20070009999-A1 | Asymmetric reduction of 1,1,1-trifluoroacetone | HOFFMANN-LA ROCHE INC. | 2007-01-11 | — | — | US | disclosed |
| US-5128252-A | Resolution of optically active esters, transesterification, lipase | CHISSO CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0384189-A2 | Optically active compound and a process for the production thereof | CHISSO CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | MAVS, EMG1, PINK1 | MGAM 4326/4885GAA 4052/4885SI 3672/4885 |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | HNMT, EMG1, API5 | MGAM 1696/4885GAA 2022/4885SI 3201/4885 |
| US-20110251289-A1 | NEW COMPOUNDS FOR THE TREATMENT OF CANCER | DUT, BAD, TYMS | MGAM 3887/4885GAA 1931/4885SI 2422/4885 |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | EMG1, HNMT, MSN | MGAM 2012/4885GAA 1769/4885SI 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.