Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989200 | 0.85 | PTGDR2 (0.39) | ALDH1A1PTGDR2MAPTKMT2APOLB | |
| SCHEMBL988296 | 0.76 | PTGS2 (0.46) | ALDH1A1KMT2APOLB | |
| SCHEMBL7829446 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL8888441 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TDP1L3MBTL1PTGDR2KMT2A | |
| SCHEMBL990491 | 0.72 | PTGS2 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL11785719 | 0.70 | PLA2G4B (0.53) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL11192482 | 0.69 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL2773278 | 0.68 | PTGDR2 (0.44) | PTGDR2KMT2A | |
| SCHEMBL7754930 | 0.67 | PTGS2 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL10291447 | 0.66 | FDPS (0.53) | ALDH1A1TDP1L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102154-A2 | BIARYL OXYACETIC ACID COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-09-10 | — | — | WO | disclosed |