SCHEMBL27754244

SCHEMBL27754244

CO[SiH2]OC.Cc1ccccc1C1(C)COC1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.32
PKM P14618 1/20 0.31
OPRM1 P35372 1/20 0.31
TSHR P16473 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27346545 0.72 TSHR (0.59) TSHRACHE
SCHEMBL21616543 0.68 HTR2A (0.35)
SCHEMBL5866512 0.68 OPRM1 (0.46) HDAC4OPRM1TSHRACHE
SCHEMBL11800826 0.67 HDAC4 (0.50) HDAC4OPRM1TSHRACHE
SCHEMBL30717248 0.67 TSHR (0.39) HDAC4OPRM1TSHRACHE
SCHEMBL6152617 0.66 HDAC4 (0.49) HDAC4OPRM1TSHRACHE
SCHEMBL24815862 0.66 CXCR5 (0.33) TSHR
Benzene SCHEMBL28837788 0.64 HDAC4 (0.47) HDAC4OPRM1
SCHEMBL21858428 0.64 OPRM1 (0.38) HDAC4OPRM1
SCHEMBL21858413 0.64 CYP2D6 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101515113-A Radioactive ray sensibility resin composition, interlayer insulating film, microlens and method of forming the same JSR CORP (JP) 2009-08-26 CN disclosed