Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858413 | 0.81 | CYP2D6 (0.32) | HTR2AKCNH2 | |
| SCHEMBL4964190 | 0.74 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1APOBEC3G | |
| SCHEMBL15525045 | 0.74 | MEN1 (0.39) | OPRM1OPRL1LMNAGAAKMT2A | |
| SCHEMBL21616543 | 0.71 | HTR2A (0.35) | HTR2AKCNH2GAAALDH1A1 | |
| SCHEMBL12023243 | 0.68 | OPRL1 (0.56) | OPRL1HTR2AALDH1A1 | |
| SCHEMBL5866515 | 0.67 | CYP2D6 (0.46) | OPRM1OPRD1OPRK1OPRL1PDK2 | |
| SCHEMBL15525070 | 0.67 | LMNA (0.43) | LMNAGAAKMT2AALDH1A1HPGD | |
| SCHEMBL22202749 | 0.66 | HTR2A (0.35) | PDK2HTR2A | |
| SCHEMBL34467580 | 0.65 | RARB (0.40) | OPRM1OPRD1OPRK1OPRL1APOBEC3G | |
| Methoxymethane SCHEMBL27638371 | 0.65 | APOBEC3G (0.50) | APOBEC3GPDCD1CD274CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-09 | — | — | US | disclosed |
| CN-112912374-A | Oxocyclobutylphenoxyquinolines and analogs | 拜耳公司 | 2021-06-04 | — | — | CN | disclosed |
| WO-2020079232-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | CBR3, CYP4X1, AOX1 | OPRM1 3990/4885OPRD1 4376/4885OPRK1 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.