Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858428 | 0.81 | OPRM1 (0.38) | HTR2AKCNH2 | |
| SCHEMBL21616543 | 0.75 | HTR2A (0.35) | HTR2AKCNH2 | |
| SCHEMBL2474639 | 0.74 | ALDH1A1 (0.33) | CYP2D6HTR2A | |
| SCHEMBL27775151 | 0.68 | TAAR1 (0.33) | — | |
| SCHEMBL21587746 | 0.67 | OPRL1 (0.44) | — | |
| SCHEMBL15525070 | 0.67 | LMNA (0.43) | — | |
| SCHEMBL22202749 | 0.66 | HTR2A (0.35) | HTR2A | |
| SCHEMBL10362617 | 0.66 | — | — | |
| SCHEMBL13471 | 0.65 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL32664646 | 0.64 | CA2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-09 | — | — | US | disclosed |
| CN-112912374-A | Oxocyclobutylphenoxyquinolines and analogs | 拜耳公司 | 2021-06-04 | — | — | CN | disclosed |
| WO-2020079232-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | CBR3, CYP4X1, AOX1 | CYP2D6 70/4885HTR2A 3684/4885KCNH2 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.