Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 8/20 | 0.75 |
| ▸ | BRAF | P15056 | 11/20 | 0.65 |
| ▸ | EGFR | P00533 | 9/20 | 0.63 |
| ▸ | CSF1R | P07333 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671596 | 0.90 | KIT (0.68) | KITBRAFEGFRCSF1R | |
| SCHEMBL588917 | 0.90 | KIT (0.93) | KITBRAFEGFRCSF1R | |
| SCHEMBL27933497 | 0.89 | KIT (0.84) | KITBRAFEGFRCSF1R | |
| SCHEMBL28062998 | 0.86 | KIT (0.76) | KITBRAFEGFRCSF1R | |
| SCHEMBL29493482 | 0.86 | KIT (1.00) | KITBRAFEGFRCSF1R | |
| SCHEMBL588975 | 0.86 | KIT (1.00) | KITBRAFEGFRCSF1R | |
| SCHEMBL19500735 | 0.86 | KIT (0.82) | KITBRAFEGFRCSF1R | |
| SCHEMBL30080656 | 0.86 | KIT (1.00) | KITBRAFEGFRCSF1R | |
| SCHEMBL15442316 | 0.85 | KIT (0.81) | KITBRAFEGFRCSF1R | |
| SCHEMBL17537391 | 0.84 | KIT (0.80) | KITBRAFEGFRCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837575-A | 3-ethynyl pyrazolo pyrimidine derivative and preparation method and application thereof | 四川大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-103044432-B | Bicyclic heteroaryl compounds | 阿里亚德医药股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-101490053-B | Monocyclic Heteroaryl Compounds | ARIAD PHARMA INC | 2013-09-11 | — | — | CN | disclosed |
| CN-103044432-A | Bicyclic heteroaryl compounds | ARIAD PHARMA INC | 2013-04-17 | — | — | CN | disclosed |
| CN-101489558-A | Acetylenic heteroaryl compounds | ARIAD PHARMA INC (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101490053-A | Monocyclic Heteroaryl Compounds | ARIAD PHARMA INC (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-101389338-A | Bicyclic heteroaryl compounds | ARIAD PHARMA INC (US) | 2009-03-18 | — | — | CN | disclosed |