Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thioxanthene SCHEMBL29398766 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL8717 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL27482326 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL28542371 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL28751085 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL27797478 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL18311802 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL31106427 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL28315422 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| Thioxanthene SCHEMBL28014365 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152109-C | Arylheterocycle substituted dibenzofuranpyran-type photochromic compound and its preparing process and usage | 中国科学院感光化学研究所 | 2004-06-02 | — | — | CN | claimed |
| CN-1152108-C | Arylheterocycle substituted naphthopyran-type photochromic compound and its preparing process and usage | 中国科学院感光化学研究所 | 2004-06-02 | — | — | CN | claimed |
| CN-1328109-A | Arylheterocycle substituted dibenzofuranpyran-type photochromic compound and its preparing process and usage | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-12-26 | — | — | CN | claimed |
| CN-1328108-A | Arylheterocycle substituted naphthopyran-type photochromic compound and its preparing process and usage | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-12-26 | — | — | CN | claimed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20100025661-A1 | Luminescent material and organic electroluminescent device using the same | JNC CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| US-7642324-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642216-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20090143222-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090131619-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| CN-1512992-A | Novel adenine derivatives | ס����ҩ��ʽ���� | 2004-07-14 | — | — | CN | disclosed |
| US-20040132748-A1 | Novel adenne derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| CN-1152109-C | Arylheterocycle substituted dibenzofuranpyran-type photochromic compound and its preparing process and usage | 中国科学院感光化学研究所 | 2004-06-02 | — | — | CN | disclosed |
| CN-1152108-C | Arylheterocycle substituted naphthopyran-type photochromic compound and its preparing process and usage | 中国科学院感光化学研究所 | 2004-06-02 | — | — | CN | disclosed |
| EP-1386923-A1 | NOVEL ADENINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| CN-1328108-A | Arylheterocycle substituted naphthopyran-type photochromic compound and its preparing process and usage | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-12-26 | — | — | CN | disclosed |
| CN-1328109-A | Arylheterocycle substituted dibenzofuranpyran-type photochromic compound and its preparing process and usage | INST PHOTOSENSITIVE CHEMISTRY CAS (CN) | 2001-12-26 | — | — | CN | disclosed |
| US-6268514-B1 | TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132748-A1 | Novel adenne derivatives | IRF3, IFNAR1, STING1 | ALDH1A1 1181/4885HPGD 2158/4885KDM4E 2790/4885 |
| US-20100025661-A1 | Luminescent material and organic electroluminescent device using the same | TRPV3, TRPC3, HVCN1 | ALDH1A1 944/4885HPGD 3560/4885KDM4E 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.