SCHEMBL27754367

SCHEMBL27754367

NCc1c[c]cc(F)c1C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.31
TIPARP Q7Z3E1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2286355 0.80
SCHEMBL27754376 0.78 NOTUM (0.34)
SCHEMBL27754365 0.78
SCHEMBL148093 0.78 NOTUM (0.30)
SCHEMBL28083157 0.76 LOXL2 (0.35) LOXL2
SCHEMBL27714251 0.72 PNMT (0.37) LOXL2
SCHEMBL27754359 0.71 LOXL2 (0.32) LOXL2
SCHEMBL2283140 0.70
SCHEMBL3166443 0.69 TAAR1 (0.43) LOXL2
SCHEMBL2282014 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101506166-B Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds BASF SE 2011-08-24 CN disclosed
CN-101506166-A Substituted 1-(azolin-2-yl)-amino-2-aryl-1-hetaryl-ethane compounds BASF SE (DE) 2009-08-12 CN disclosed