Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.35 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2774871 | 0.78 | DPP4 (0.42) | DPP4DPP7EPHX2 | |
| SCHEMBL2776630 | 0.74 | SRD5A1 (0.46) | EPHX2 | |
| SCHEMBL2777057 | 0.74 | SRD5A1 (0.46) | EPHX2 | |
| SCHEMBL12283148 | 0.73 | GPR119 (0.50) | PDE4BOPRK1GPR119 | |
| SCHEMBL28528054 | 0.73 | CYP3A4 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL2774798 | 0.72 | CYP3A4 (0.45) | DPP4KMT2A | |
| SCHEMBL27425180 | 0.71 | MEN1 (0.46) | PDE4BEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL6522457 | 0.69 | DPP4 (0.33) | DPP4DPP7EPHX2ALDH1A1MEN1 | |
| SCHEMBL21448827 | 0.69 | DPP7 (0.36) | DPP4DPP7ALDH1A1 | |
| SCHEMBL18270916 | 0.69 | DPP7 (0.36) | DPP4DPP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |