SCHEMBL277555

SCHEMBL277555

CC(Nc1cccc2cc3cc4cc5ccc6cc7cc8cc9ccccc9cc8cc7cc6c5cc4cc3cc12)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
KDM4E B2RXH2 4/20 0.43
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
GAA P10253 2/20 0.43
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
TRPV1 Q8NER1 2/20 0.39
AKR1B1 P15121 1/20 0.39
TNNI3 P19429 1/20 0.38
TNNT2 P45379 1/20 0.38
TNNC1 P63316 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CCKAR P32238 1/20 0.38
LMNA P02545 1/20 0.38
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL414684 0.96 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL1115756 0.96 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL29414377 0.96 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL837924 0.96 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL42287 0.82 CA12 (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL29478385 0.82 CA12 (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL42286 0.82 CA12 (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL298855 0.82 CA12 (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL409050 0.82 CA12 (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL29367675 0.82 CA12 (0.54) ALDH1A1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228985-A1 MODIFIED SEED OIL CONTENT IN PLANTS PIONEER HI-BRED INTERNATIONAL, INC (US) 2024-07-11 US claimed
CN-116953228-A Method and reagent for identifying antibody combined with mutant antigen 广东菲鹏生物有限公司 2023-10-27 CN claimed
WO-2022246387-A1 MODIFIED SEED OIL CONTENT IN PLANTS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2022-11-24 WO claimed
US-20220186258-A1 MODIFIED AAV VECTORS THAT DAMPEN THE HUMORAL IMMUNE RESPONSE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-06-16 US claimed
US-20210371472-A1 INFLUENZA VIRUS HEMAGGLUTININ MUTANTS ARAMIS BIOTECHNOLOGIES INC. (CA) 2021-12-02 US claimed
US-20210340184-A1 INFLUENZA VIRUS HEMAGGLUTINIIN MUTANTS ARAMIS BIOTECHNOLOGIES INC. (CA) 2021-11-04 US claimed
US-20210221853-A1 INFLUENZA VIRUS HEMAGGLUTININ MUTANTS ARAMIS BIOTECHNOLOGIES INC. (CA) 2021-07-22 US claimed
EP-3814508-A1 INFLUENZA VIRUS HEMAGGLUTININ MUTANTS Medicago Inc. (CA) 2021-05-05 EP claimed
EP-3814507-A1 INFLUENZA VIRUS HEMAGGLUTININ MUTANTS Medicago Inc. (CA) 2021-05-05 EP claimed
EP-3814509-A1 INFLUENZA VIRUS HEMAGGLUTININ MUTANTS Medicago Inc. (CA) 2021-05-05 EP claimed
WO-2007074456-A2 INHIBITION OF CXCR4 AND/OR CELL MOTILITY BY PHENYLALANINE, CYSTEINE OR PEPTIDES CONTAINING SAID AMINOACIDS YEDA RESEARCH AND DEVELOPMENT CO.LTD. (IL) 2007-07-05 WO claimed
JP-2007511536-A 2007-05-10 JP claimed
CN-1295335-C A gene coding for a protein regulating aureobasidin sensitivity TAKARA SHUZO CO (JP) 2007-01-17 CN claimed
EP-1708690-A2 TREATMENT OF PHENYLKETONURIAS WITH BH4 BioMarin Pharmaceutical Inc. (US) 2006-10-11 EP claimed
US-20060040946-A1 Methods and compositions for the treatment of metabolic disorders BIOMARIN PHARMACEUTICAL INC. (US) 2006-02-23 US claimed
WO-2005049000-A2 TREATMENT OF PHENYLKETONURIAS WITH BH4 BIOMARIN PHARMACEUTICAL INC. (US) 2005-06-02 WO claimed
US-20040131609-A1 Ultra high affinity neutralizing antibodies APPLIED MOLECULAR EVOLUTION, INCORPORATED 2004-07-08 US claimed
EP-1265928-A1 ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES MEDIMMUNE, INC. (US) 2002-12-18 EP claimed
US-20020164326-A1 Ultra high affinity neutralizing antibodies MEDIMMUNE, LLC 2002-11-07 US claimed
WO-2001055217-A1 ULTRA HIGH AFFINITY NEUTRALIZING ANTIBODIES MEDIMMUNE, INC. (US) 2001-08-02 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060040946-A1 Methods and compositions for the treatment of metabolic disorders PAH, BHMT, FAH ALDH1A1 1048/4885MEN1 2539/4885KMT2A 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.