Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.41 |
| ▸ | GABRD | O14764 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.41 |
| ▸ | GABRE | P78334 | 4/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2161703 | 0.89 | PARP1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL75798 | 0.87 | ALDH1A1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL580101 | 0.86 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17911667 | 0.85 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1832021 | 0.84 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL10946506 | 0.84 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Cyclohexane SCHEMBL7802327 | 0.82 | GABRP (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Phthalic Acid SCHEMBL10963447 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ACLCN2 | |
| Phthalic Acid SCHEMBL29429444 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ACLCN2 | |
| SCHEMBL2498889 | 0.79 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103382197-A | N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same | CELGENE CORP | 2013-11-06 | — | — | CN | disclosed |
| CN-101534820-A | N-methylaminomethylisoindole compounds and compositions comprising and methods of using the same | CELGENE CORP (US) | 2009-09-16 | — | — | CN | disclosed |