Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19284356 | 0.82 | PADI4 (0.41) | NOTUM | |
| SCHEMBL19301796 | 0.78 | PADI4 (0.42) | NOTUMKDM2BPTGER4MAPTMTOR | |
| SCHEMBL19284354 | 0.78 | LMNA (0.45) | GRIN1GRIN2BPTGER4 | |
| SCHEMBL27736521 | 0.74 | MEN1 (0.40) | CNR1PIK3CAMTOR | |
| SCHEMBL15180531 | 0.73 | MAP4K4 (0.41) | KDM2B | |
| SCHEMBL27736515 | 0.73 | L3MBTL1 (0.41) | CNR1PIK3CAMTOR | |
| SCHEMBL17868428 | 0.72 | MAP4K4 (0.41) | — | |
| SCHEMBL19301627 | 0.71 | KDM4E (0.43) | NOTUMGRIN1GRIN2BMAPK14MAPT | |
| Hydrochloric Acid SCHEMBL27294605 | 0.71 | MAP4K4 (0.40) | — | |
| SCHEMBL19284323 | 0.70 | PADI4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101405277-A | Dicarbonylic compounds with antibacterial activity | SALVAT LAB SA (ES) | 2009-04-08 | — | — | CN | disclosed |