Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.48 |
| ▸ | BCL3 | P20749 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28944630 | 0.86 | TAS1R3 (0.49) | KDM4ERAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL14368778 | 0.86 | TAS1R3 (0.49) | KDM4ERAB9AALDH1A1L3MBTL1GAA | |
| SCHEMBL14368809 | 0.84 | F10 (0.49) | CCR3NPC1ACKR3 | |
| SCHEMBL27778277 | 0.84 | F10 (0.49) | CCR3NPC1ACKR3 | |
| SCHEMBL14392660 | 0.84 | CCR3 (0.40) | CCR3HTTKDM4ENPC1RAB9A | |
| SCHEMBL4429053 | 0.83 | CCR3 (0.50) | CCR3HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL14368806 | 0.83 | CCR3 (0.50) | CCR3HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL14392662 | 0.82 | CCR3 (0.44) | CCR3 | |
| SCHEMBL14368669 | 0.81 | SSTR3 (0.55) | CCR3NPC1RAB9A | |
| SCHEMBL27757345 | 0.81 | SSTR3 (0.55) | CCR3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |