Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368778 | 1.00 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2ALDH1A1MAPT | |
| SCHEMBL27757451 | 0.86 | CCR3 (0.48) | ALDH1A1KDM4EGAARAB9AEPHX2 | |
| SCHEMBL14392660 | 0.84 | CCR3 (0.40) | TAS1R3TAS1R1TAS1R2ALDH1A1LMNA | |
| SCHEMBL14368806 | 0.83 | CCR3 (0.50) | ALDH1A1GAARAB9AKMT2A | |
| SCHEMBL4429053 | 0.83 | CCR3 (0.50) | ALDH1A1GAARAB9AKMT2A | |
| SCHEMBL27757300 | 0.81 | CHRNA7 (0.51) | ALDH1A1MAPTF10KDM4ERAB9A | |
| SCHEMBL14368703 | 0.81 | CHRNA7 (0.51) | ALDH1A1MAPTF10KDM4ERAB9A | |
| SCHEMBL14392352 | 0.81 | CHRNA7 (0.51) | ALDH1A1MAPTF10KDM4ERAB9A | |
| SCHEMBL14368754 | 0.81 | NPC1 (0.48) | TAS1R3TAS1R1TAS1R2HPGDRAB9A | |
| SCHEMBL27778286 | 0.80 | CNR1 (0.43) | TAS1R3TAS1R1TAS1R2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |