Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226759 | 0.74 | NPC1 (0.55) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL3676457 | 0.72 | NPC1 (0.45) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL3213503 | 0.71 | PTGS2 (0.50) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL3223391 | 0.71 | MAPT (0.76) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL3219976 | 0.71 | KMT2A (0.44) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL28748681 | 0.71 | MEN1 (0.59) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL28748631 | 0.70 | MEN1 (0.59) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL5077845 | 0.70 | MEN1 (0.57) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL1712561 | 0.70 | ADORA3 (0.54) | NPC1RAB9AKMT2AMAPTMEN1 | |
| SCHEMBL28544979 | 0.70 | ESR2 (0.51) | NPC1RAB9AKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420952-A | Treatment of duchenne muscular dystrophy | SUMMIT CORP PLC (GB) | 2009-04-29 | — | — | CN | disclosed |