SCHEMBL3219976

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3213503	0.85	PTGS2 (0.50)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL3676457	0.83	NPC1 (0.45)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL3223391	0.72	MAPT (0.76)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL3226759	0.72	NPC1 (0.55)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL28748681	0.72	MEN1 (0.59)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL3219346	0.72	ALDH1A1 (0.51)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL28748631	0.71	MEN1 (0.59)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL27759239	0.71	NPC1 (0.40)	KMT2AMEN1NPC1RAB9AMAPT
	SCHEMBL217302	0.70	ALDH1A1 (0.54)	KMT2AMEN1MAPTPTGS2CA12
	SCHEMBL5077845	0.68	MEN1 (0.57)	KMT2AMEN1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.