Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759458 | 1.00 | SLC6A1 (0.30) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL27537660 | 0.92 | KDM4E (0.38) | SLC6A1SLC6A11SLC6A13KDM4EMAPT | |
| SCHEMBL27915636 | 0.80 | SLC6A1 (0.43) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL27664282 | 0.80 | SLC6A1 (0.43) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL27934254 | 0.80 | SLC6A1 (0.43) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL27905600 | 0.78 | CA1 (0.39) | — | |
| SCHEMBL27888905 | 0.78 | CA1 (0.39) | — | |
| SCHEMBL27568926 | 0.76 | GABRA5 (0.34) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| SCHEMBL12536233 | 0.76 | GBA1 (0.34) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 | |
| Methyl Alcohol SCHEMBL27528171 | 0.75 | GABRA5 (0.33) | SLC6A1GABRA5GABRB2SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |