Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.31 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27888905 | 1.00 | CA1 (0.39) | CA1CA2CA4TSHRPTGS1 | |
| SCHEMBL27682585 | 0.85 | SYK (0.30) | — | |
| SCHEMBL27682586 | 0.85 | SYK (0.30) | — | |
| SCHEMBL28018666 | 0.84 | CA1 (0.44) | CA1CA2CA4TSHR | |
| SCHEMBL27537660 | 0.82 | KDM4E (0.38) | TSHR | |
| SCHEMBL28102273 | 0.81 | BTK (0.30) | — | |
| SCHEMBL27520063 | 0.79 | ALOX5 (0.37) | — | |
| SCHEMBL27759460 | 0.78 | SLC6A1 (0.30) | — | |
| SCHEMBL9227258 | 0.77 | ALOX5 (0.39) | — | |
| SCHEMBL27766894 | 0.75 | ALOX5 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858782-A | 4 - [cycloalkyloxy (hetero) arylamino] thieno [2, 3 - d] pyrimidines having mnkl/ mnk2 inhibiting activity for pharmaceutical compositions | BOEHRINGER INGELHEIM INT | 2013-01-02 | — | — | CN | disclosed |