Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CCR1 | P32246 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774368 | 0.87 | EPHX2 (0.50) | EPHX2ALDH1A1CCR1PREPMAPT | |
| SCHEMBL2776309 | 0.86 | ACACB (0.46) | ALDH1A1CCR1MAPTNAMPT | |
| SCHEMBL2777506 | 0.85 | ALDH1A1 (0.44) | EPHX2ALDH1A1CCR1PREPKCNH2 | |
| SCHEMBL2774934 | 0.83 | CCR1 (0.46) | ALDH1A1CCR1KCNH2 | |
| SCHEMBL2775312 | 0.82 | ALDH1A1 (0.47) | EPHX2ALDH1A1CCR1HTTSPR | |
| SCHEMBL2775675 | 0.82 | EPHX2 (0.52) | EPHX2ALDH1A1HTTSPRMAPT | |
| SCHEMBL2779095 | 0.82 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2776130 | 0.82 | GPR119 (0.50) | ALDH1A1CCR1 | |
| SCHEMBL2774679 | 0.82 | EPHX2 (0.51) | EPHX2ALDH1A1CCR1NAMPTKCNH2 | |
| Hydrochloric Acid SCHEMBL2775304 | 0.81 | EPHX2 (0.51) | EPHX2ALDH1A1HTTSPRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |