SCHEMBL27760409

SCHEMBL27760409

O=C(O)c1[nH]c2cccc(C(=O)O)c2c1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.54
GPR17 Q13304 3/20 0.44
PBRM1 Q86U86 2/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
ALOX15 P16050 1/20 0.41
CYP1A2 P05177 1/20 0.41
NAPRT Q6XQN6 1/20 0.40
DHODH Q02127 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9655179 0.85 AKR1C3 (0.53) PARP1PBRM1HSD17B10ALDH1A1KDM4E
SCHEMBL30455376 0.74 PARP1 (0.73) PARP1PBRM1HSD17B10ALDH1A1KDM4E
SCHEMBL4478535 0.74 PARP1 (0.54) PARP1PBRM1HSD17B10ALDH1A1KDM4E
SCHEMBL2183473 0.74 PARP1 (0.73) PARP1PBRM1HSD17B10ALDH1A1KDM4E
SCHEMBL30749415 0.74 PARP1 (0.73) PARP1PBRM1HSD17B10ALDH1A1KDM4E
SCHEMBL87871 0.73 KDM4E (0.65) HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL212687 0.73 PARP1 (0.61) PARP1PBRM1HSD17B10ALDH1A1KDM4E
SCHEMBL5799164 0.71 MEN1 (0.41) GPR17HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL29350550 0.70 IMPDH2 (0.47) GPR17ALDH1A1KDM4EHPGD
SCHEMBL48966 0.70 IMPDH2 (0.47) GPR17ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101616804-B Radiation-sensitive compositions and elements with alkaline development enhancers EASTMAN KODAK CO 2012-12-12 CN disclosed
CN-102132217-A Processing of positive-working lithographic printing plate precursors EASTMAN KODAK CO 2011-07-20 CN disclosed
CN-102056743-A Imageable elements for providing waterless printing plates EASTMAN KODAK CO 2011-05-11 CN disclosed
CN-101426649-B Positive imageable element, method for forming image using same and imaging element obtained therefrom EASTMAN KODAK CO 2010-09-08 CN disclosed
CN-101616804-A Radiation-sensitive compositions and elements with alkaline development enhancers EASTMAN KODAK CO 2009-12-30 CN disclosed
CN-101426649-A Multilayer imageable element with improved chemical resistance EASTMAN KODAK CO (US) 2009-05-06 CN disclosed