Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350550 | 1.00 | IMPDH2 (0.47) | IMPDH2IMPDH1GPR17MEN1KMT2A | |
| Water SCHEMBL28121843 | 0.98 | IMPDH2 (0.46) | IMPDH2IMPDH1GPR17MEN1KMT2A | |
| SCHEMBL28718284 | 0.84 | IMPDH2 (0.46) | IMPDH2IMPDH1GPR17MEN1KMT2A | |
| SCHEMBL27396667 | 0.82 | GPR17 (0.60) | GPR17MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8112949 | 0.80 | CA12 (0.50) | IMPDH2IMPDH1MEN1KMT2AKDM4E | |
| SCHEMBL1490130 | 0.74 | IMPDH2 (0.55) | IMPDH2IMPDH1MEN1KMT2AKDM4E | |
| SCHEMBL7461151 | 0.74 | IMPDH2 (0.43) | IMPDH2IMPDH1MEN1KMT2AKDM4E | |
| SCHEMBL62193 | 0.73 | KDM4E (0.62) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL30366683 | 0.73 | KDM4E (0.62) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL3886120 | 0.73 | IMPDH2 (0.71) | IMPDH2IMPDH1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 572 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240000694-A1 | Methods and Materials for Matching Chemistry of Individuals and Human Melanin | UNIV NORTHWESTERN (US) | 2024-01-04 | — | — | US | claimed |
| CN-116500175-A | Method for measuring content of melanin precursor and application | 珠海市丝域生物科技有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-113520913-B | Hair dye containing silica nanoparticles loaded with dihydroxyindole carboxylic acid | 绍兴孚原生物科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-113520913-A | Hair dye containing silica nanoparticles loaded with dihydroxyindole carboxylic acid | 绍兴孚原生物科技有限公司 | 2021-10-22 | — | — | CN | claimed |
| US-7758861-B2 | Dye-sulfenates for dual phototherapy | MALLINCKRODT INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-1409482-B1 | DYE-SULFENATES FOR DUAL PHOTOTHERAPY | MALLINCKRODT INC (US) | 2009-12-30 | — | — | EP | claimed |
| US-20080275017-A1 | AROMATIC SULFENATES FOR TYPE I PHOTOTHERAPY | MALLINCKRODT LLC | 2008-11-06 | — | — | US | claimed |
| US-7427657-B1 | absorb low-energy ultraviolet, visible, or near-infrared (NIR) region of the electromagnetic spectrum; phototherapeutic effect is caused by direct interaction of free radicals, the reactive intermediate produced upon photofragmentation of the sulfenate moiety, with the tissue of interest | MALLINCKRODT INC. (US) | 2008-09-23 | — | — | US | claimed |
| EP-1405627-B1 | Antipenetrating hair pretreatment composition based on polyethelenoxide polymer(s) and process using said composition for limiting skin penetration by colourants | OREAL (FR) | 2008-04-30 | — | — | EP | claimed |
| EP-1442465-A4 | COMPONENTS BASED ON MELANIN AND MELANIN-LIKE BIO-MOLECULES AND PROCESSES FOR THEIR PRODUCTION | UNIV QUEENSLAND (AU) | 2007-08-29 | — | — | EP | claimed |
| EP-0820275-A4 | COSMETIC MELANINS | UNIV YALE (US) | 2000-03-08 | — | — | EP | claimed |
| US-5744125-A | OXIDATIVE POLYMERIZATION OF PRECURSORS THAT ENHANCE SUBSTANTIVITY OR ADHERENCE TO HAIR OR SKIN | YALE UNIVERSITY (US) | 1998-04-28 | — | — | US | claimed |
| EP-0820275-A1 | COSMETIC MELANINS | YALE UNIVERSITY (US) | 1998-01-28 | — | — | EP | claimed |
| US-5618519-A | USEFUL FOR PROVIDING A NATURALLY-APPEARING TAN TO MAMMALIAN SKIN AND HAIR; PRODUCED BY POLYMERIZING DIHYDROXYINDOLE CARBOXYLIC ACID WITH AERATION | YALE UNIVERSITY (US) | 1997-04-08 | — | — | US | claimed |
| WO-1996025920-A9 | COSMETIC MELANINS | — | 1996-10-31 | — | — | WO | claimed |
| WO-1996025920-A1 | COSMETIC MELANINS | YALE UNIVERSITY (US) | 1996-08-29 | — | — | WO | claimed |
| US-5384116-A | Synthetic melanin as a sunscreen and tanning agent | YALE UNIVERSITY (US) | 1995-01-24 | — | — | US | claimed |
| US-5227459-A | Synthetic melanin | YALE UNIVERSITY (US) | 1993-07-13 | — | — | US | claimed |
| US-5218079-A | From dihydroxyindolecarboxylic acid | YALE UNIVERSITY (US) | 1993-06-08 | — | — | US | claimed |
| US-5216116-A | Polymerizing a dihydroxyindole-carboxylic acid in the presence of a sulfhydryl compound | YALE UNIVERSITY (US) | 1993-06-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000694-A1 | Methods and Materials for Matching Chemistry of Individuals and Human Melanin | TYR, MC1R, HLA-C | IMPDH2 2596/4885IMPDH1 2395/4885GPR17 4337/4885 |
| US-20080275017-A1 | AROMATIC SULFENATES FOR TYPE I PHOTOTHERAPY | TYR, SULT1A1, TPST2 | IMPDH2 2313/4885IMPDH1 903/4885GPR17 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.