Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B3GNT2 | Q9NY97 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27739909 | 0.89 | B3GNT2 (0.64) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL20529030 | 0.81 | B3GNT2 (0.74) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL891359 | 0.78 | KDM4E (0.47) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL27952176 | 0.77 | B3GNT2 (0.48) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL20529258 | 0.77 | KMT2A (0.55) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL20529229 | 0.75 | KDM4E (0.50) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7436018 | 0.75 | B3GNT2 (0.47) | B3GNT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29848351 | 0.72 | BRD3 (0.43) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL27311007 | 0.72 | MTNR1A (0.50) | KDM4EKMT2AMEN1 | |
| SCHEMBL8121054 | 0.72 | B3GNT2 (0.43) | B3GNT2KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420942-B | Small-molecule modulators of TRP-P8 activity | DENDREON CORP | 2014-03-12 | — | — | CN | disclosed |
| CN-101420942-A | Small-molecule modulators of TRP-P8 activity | DENDREON CORP (US) | 2009-04-29 | — | — | CN | disclosed |