SCHEMBL891359

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL897551	0.90	B3GNT2 (0.55)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL891295	0.86	DYRK1A (0.49)	HSD17B10BRD4DRD2
	SCHEMBL15173247	0.84	B3GNT2 (0.53)	KDM4EALDH1A1GAAHPGDHSD17B10
	SCHEMBL13315300	0.84	KDM4E (0.46)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL891197	0.82	BCHE (0.49)	ALDH1A1HPGDKMT2AHTTTDP1
	SCHEMBL27760417	0.78	B3GNT2 (0.50)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL20529258	0.78	KMT2A (0.55)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL5171827	0.77	BCHE (0.45)	ALDH1A1HPGDKMT2AHTTTDP1
	SCHEMBL13011486	0.77	CNR2 (0.56)	ALDH1A1HPGDBRD4DRD2
	SCHEMBL4915938	0.77	ALDH1A1 (0.47)	KDM4EALDH1A1GAAHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.