Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | B3GNT2 | Q9NY97 | 4/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7214732 | 0.90 | PARP1 (0.45) | B3GNT2KIF11RAB9ANPC1CREBBP | |
| SCHEMBL31709866 | 0.81 | AKT2 (0.44) | B3GNT2 | |
| SCHEMBL319785 | 0.81 | DAO (0.52) | B3GNT2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL29848246 | 0.80 | ALDH1A1 (0.42) | B3GNT2RAB9ANPC1CREBBPKDM4E | |
| SCHEMBL4948766 | 0.79 | KCNQ3 (0.40) | B3GNT2KIF11KDM4EKMT2AGAA | |
| SCHEMBL7230617 | 0.79 | HSP90AA1 (0.43) | B3GNT2KIF11KDM4EALDH1A1KMT2A | |
| SCHEMBL29847378 | 0.78 | HSD11B1 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL7214021 | 0.78 | PARP1 (0.44) | B3GNT2KIF11RAB9ANPC1CREBBP | |
| SCHEMBL14934065 | 0.78 | MAOB (0.38) | B3GNT2KDM4EALDH1A1GABRA1GABRG2 | |
| SCHEMBL1759187 | 0.77 | CREBBP (0.51) | B3GNT2KIF11RAB9ANPC1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012600-A9 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS INC (US) | 2002-09-12 | — | — | WO | disclosed |
| WO-2001012600-A1 | INHIBITORS OF FACTOR Xa | COR THERAPEUTICS, INC. (US) | 2001-02-22 | — | — | WO | disclosed |