Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28039586 | 0.87 | ALDH1A1 (0.36) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| Acetaldehyde SCHEMBL27778138 | 0.86 | PNMT (0.51) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| SCHEMBL427407 | 0.85 | PNMT (0.58) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| SCHEMBL31378863 | 0.85 | PNMT (0.58) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| SCHEMBL27632113 | 0.81 | PNMT (0.51) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| Chloroform SCHEMBL7695703 | 0.79 | PNMT (0.53) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| Tert-Butyl Formate SCHEMBL27928392 | 0.77 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL29581896 | 0.76 | PNMT (0.51) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| SCHEMBL395008 | 0.76 | PNMT (0.51) | PNMTADRA2AMAPTALDH1A1NPC1 | |
| Tert-Butyl Formate SCHEMBL28007057 | 0.76 | TDP2 (0.42) | PNMTADRA2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437810-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2009-05-20 | — | — | CN | disclosed |