Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.46 |
| ▸ | MTOR | P42345 | 7/20 | 0.44 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748485 | 0.86 | SRC (0.47) | GAAALDH1A1PIK3CAPIK3R1MTOR | |
| SCHEMBL8062292 | 0.81 | PIK3CA (0.58) | PIK3CAPIK3R1MTORPIK3CDPIK3CB | |
| SCHEMBL7952861 | 0.79 | PIK3CA (0.58) | PIK3CAPIK3R1MTORSRCPIK3CD | |
| SCHEMBL27918121 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1HPGDSRCKMT2A | |
| SCHEMBL8079836 | 0.78 | PIK3CA (0.59) | PIK3CAPIK3R1MTORPIK3CDPIK3CB | |
| SCHEMBL17150871 | 0.77 | TP53 (0.53) | KMT2AKIT | |
| SCHEMBL8826341 | 0.77 | IKBKB (0.52) | GAAKDM4EPIK3CAPIK3R1MTOR | |
| SCHEMBL31069504 | 0.77 | SRC (0.58) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL2776064 | 0.76 | GAA (0.53) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL3131779 | 0.75 | SRC (0.69) | SRCABL1EGFRERBB2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025226831-A1 | PURINE COVALENT BASED CDK12 INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |