Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.45 |
| ▸ | MTOR | P42345 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13650791 | 0.74 | CTSK (0.61) | NUDT1POLBNOS1IKBKBGAA | |
| SCHEMBL19548102 | 0.71 | NUDT1 (0.63) | NUDT1PIK3CAMTORPOLBNOS1 | |
| SCHEMBL13650825 | 0.71 | MAPT (0.54) | NUDT1PIK3CAMTORPOLBNOS1 | |
| SCHEMBL13650785 | 0.71 | NUDT1 (0.54) | NUDT1PIK3CAMTORPOLBNOS1 | |
| SCHEMBL18194315 | 0.70 | PIK3CA (0.62) | NUDT1PIK3CAMTORPOLBNOS1 | |
| SCHEMBL3657011 | 0.70 | PNP (0.54) | PIK3CAMTORMEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL17822432 | 0.69 | NUDT1 (0.61) | NUDT1PIK3CAMTORPOLBNOS1 | |
| SCHEMBL9643516 | 0.69 | GAA (0.56) | NUDT1PIK3CAMTORPOLBNOS1 | |
| SCHEMBL25252135 | 0.69 | NUDT1 (0.47) | NUDT1NOS1MAP2K7HRH4CRHBP | |
| SCHEMBL3765089 | 0.69 | NOS1 (0.59) | NUDT1PIK3CAMTORNOS1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790877-B2 | Antisense oligonucleotides with increased RNase sensitivity | GEN-PROBE, INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1019539-A4 | COMBINATORIAL ANTISENSE LIBRARY | GEN PROBE INC (US) | 2005-03-09 | — | — | EP | disclosed |
| EP-1019539-A1 | COMBINATORIAL ANTISENSE LIBRARY | Oasis Biosciences, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999018238-A1 | COMBINATORIAL ANTISENSE LIBRARY | OASIS BIOSCIENCES, INC. (US) | 1999-04-15 | — | — | WO | disclosed |