SCHEMBL27761502

SCHEMBL27761502

NC(=Cc1ccccc1)P(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MCL1 Q07820 1/20 0.44
FBP1 P09467 3/20 0.42
AKR1C3 P42330 1/20 0.42
NR1I2 O75469 1/20 0.42
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
AKR1C1 Q04828 1/20 0.41
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA5A P35218 1/20 0.39
ALOX15 P16050 1/20 0.38
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15668275 0.78 MCL1 (0.49) TSHRALDH1A1MCL1FBP1AKR1C3
SCHEMBL9246618 0.77 NR1I2 (0.53) TSHRALDH1A1FBP1AKR1C3NR1I2
SCHEMBL181652 0.73 ALDH1A1 (0.56) TSHRALDH1A1MCL1FBP1AKR1C3
SCHEMBL9001674 0.72 AKR1C1 (0.48) TSHRALDH1A1AKR1C3NR1I2AKR1C1
SCHEMBL8595072 0.72 TSHR (0.41) TSHRALDH1A1MCL1FBP1AKR1C3
SCHEMBL1579379 0.72 AKR1C1 (0.48) TSHRALDH1A1AKR1C3NR1I2AKR1C1
SCHEMBL2223295 0.72 AKR1C3 (0.50) TSHRALDH1A1MCL1AKR1C3NR1I2
SCHEMBL2223293 0.72 AKR1C3 (0.50) TSHRALDH1A1MCL1AKR1C3NR1I2
Phosphoric Acid SCHEMBL29150326 0.72 TSHR (0.41) TSHRALDH1A1MCL1FBP1AKR1C3
Phosphoric Acid SCHEMBL3676597 0.71 AKR1C1 (0.61) ALDH1A1MCL1AKR1C3AKR1C1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101421392-A Use of indanoyl amide to stimulate secondary metabolism in taxus sp PHYTON BIOTECH INC (US) 2009-04-29 CN disclosed