Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246618 | 0.76 | NR1I2 (0.53) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 | |
| SCHEMBL27761502 | 0.72 | TSHR (0.47) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 | |
| Phosphoric Acid SCHEMBL28335598 | 0.72 | ESR1 (0.61) | TSHRALDH1A1AKR1C1PRMT1ESR1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28411197 | 0.72 | HDAC1 (0.56) | ALDH1A1CYP2C9RECQL | |
| (Z)-1,2-Diphenylethene SCHEMBL3647896 | 0.72 | HDAC1 (0.56) | ALDH1A1CYP2C9RECQL | |
| SCHEMBL8595072 | 0.71 | TSHR (0.41) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 | |
| SCHEMBL2223293 | 0.71 | AKR1C3 (0.50) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 | |
| SCHEMBL9001674 | 0.71 | AKR1C1 (0.48) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 | |
| SCHEMBL2223295 | 0.71 | AKR1C3 (0.50) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 | |
| SCHEMBL1579379 | 0.71 | AKR1C1 (0.48) | TSHRALDH1A1AKR1C3NR1I2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117254057-A | High-strength high-proton-conductivity proton exchange membrane for fuel cell and preparation method thereof | 周先富 | 2023-12-19 | — | — | CN | claimed |
| CN-117254057-A | High-strength high-proton-conductivity proton exchange membrane for fuel cell and preparation method thereof | 周先富 | 2023-12-19 | — | — | CN | disclosed |
| CN-117254057-A | High-strength high-proton-conductivity proton exchange membrane for fuel cell and preparation method thereof | 周先富 | 2023-12-19 | — | — | CN | disclosed |