Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | CDK4 | P11802 | 4/20 | 0.36 |
| ▸ | CCND1 | P24385 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188217 | 0.84 | HTR2C (0.61) | HTR2AHTR2CHTR6CDK4CCND1 | |
| SCHEMBL694594 | 0.82 | CDK4 (0.41) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL5814894 | 0.80 | CDK4 (0.44) | HTR2AHTR2CCDK4CCND1POLB | |
| SCHEMBL6754186 | 0.79 | HTR2A (0.50) | HTR2AHTR2CCDK4CCND1NOS3 | |
| SCHEMBL189124 | 0.79 | CDK4 (0.35) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL2036331 | 0.78 | HTR2A (0.70) | SCN9AHTR2AHTR2CHTR6CDK4 | |
| SCHEMBL1450476 | 0.76 | CDK4 (0.41) | HTR2AHTR2CCDK4CCND1 | |
| SCHEMBL27382849 | 0.76 | CDK4 (0.41) | HTR2AHTR2CHTR6CDK4CCND1 | |
| SCHEMBL3198506 | 0.75 | GLO1 (0.39) | HTR2AHTR2CHTR6CDK4CCND1 | |
| SCHEMBL16719793 | 0.74 | HTR2A (0.40) | HTR2AHTR2CCDK4CCND1HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100558355-C | Indole-5 sulfamide derivative and preparation and its purposes as the 5-HT-6 regulator | ESTEVE LABOR DR (ES) | 2009-11-11 | — | — | CN | disclosed |