Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761880 | 0.88 | METAP1 (0.65) | METAP1TDP1L3MBTL1TDP2S100A4 | |
| SCHEMBL6905130 | 0.88 | METAP1 (0.65) | METAP1TDP2S100A4MAOAMAOB | |
| SCHEMBL23294539 | 0.86 | METAP1 (0.44) | METAP1TDP2S100A4ITGA1HSP90AA1 | |
| SCHEMBL4254618 | 0.86 | METAP1 (0.71) | METAP1TDP1L3MBTL1TDP2S100A4 | |
| SCHEMBL24730416 | 0.82 | CHEK2 (0.47) | METAP1TDP1L3MBTL1TDP2S100A4 | |
| SCHEMBL6018153 | 0.82 | METAP1 (0.47) | METAP1TDP2HSP90AA1PARP10PARP11 | |
| SCHEMBL5345106 | 0.82 | TDP1 (0.66) | METAP1TDP1L3MBTL1S100A4MAOA | |
| SCHEMBL10691369 | 0.82 | METAP1 (0.71) | METAP1TDP2S100A4MAOAMAOB | |
| SCHEMBL10057541 | 0.82 | TDP1 (0.63) | METAP1TDP1L3MBTL1TDP2S100A4 | |
| SCHEMBL6899110 | 0.81 | MAOA (0.67) | METAP1TDP1L3MBTL1S100A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |